I wonder if homo sapiens will ever be replaced
We are being, continually, through evolution. Look at the so-called 'diseases' caused by environmental incompatibilities, like lactose intolerance and gluten intolerance, caused by major changes in human diet at some time in the past: although the population as a whole benefits, there are those who do not and whose breeding success is compromised (breeding success, here, being the survival of young to maturity). That leaves those who thrive on that diet at an advantage over those who do not.