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 Topic: Study finds 1,317 knocked-out genes in DNA samples from Pakistanis

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  • Study finds 1,317 knocked-out genes in DNA samples from Pakistanis
     OP - July 04, 2017, 01:38 PM
    Quote
    Research published in the journal Nature has analysed the DNA of 10,503 Pakistanis who were participating in a Pakistan Risk of Myocardial Infarction Study (PROMIS) and discovered 1,317 disabled or “knocked-out” genes.

    People who are natural knockouts, that is, they were born missing one or more genes without any obvious medical problems are few and far between.

    Humans inherit two copies of every gene – one from the mother and one from the father.

    If one copy is damaged or inactivated, then the presence of the other fully functional copy may help alleviate most problems.

    However, if the parents are biologically related, then the chances of inheriting two inactivated copies are much higher.

    The person with two inactivated copies may not have the functioning protein at all and will be a natural knockout for that specific gene.

    The high number of human knockouts found in the country is due to the cultural tradition of cousin marriages that is prevalent here.

    A search for human knockouts has also been conducted in other countries including Iceland and the United Kingdom.
    ...

    https://www.dawn.com/news/1343179/study-finds-1317-knocked-out-genes-in-dna-samples-from-pakistanis
    "Life is not a matter of holding good cards, but of playing a poor hand well."
    - Robert Louis Stevenson
  • Study finds 1,317 knocked-out genes in DNA samples from Pakistanis
     Reply #1 - July 05, 2017, 12:22 AM
    I'd be more interested in how this compares to the human race as a whole.
    `But I don't want to go among mad people,' Alice remarked.
     `Oh, you can't help that,' said the Cat: `we're all mad here. I'm mad.  You're mad.'
     `How do you know I'm mad?' said Alice.
     `You must be,' said the Cat, `or you wouldn't have come here.'
  • Study finds 1,317 knocked-out genes in DNA samples from Pakistanis
     Reply #2 - July 05, 2017, 12:46 AM
    Good point QSE.
    Quote from: yeezevee on February 11, 2016, 02:05 PM
    how fuck works without shit??


    Let's Play Chess!

    harakaat, friend, RIP
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